Kasabonika Lake First Nation or Kasabonika First Nation is an Oji-Cree First Nation located north of Sioux Lookout, Ontario. There are no roads into the community and the only access is through Kasabonika Airport. It is part of the Shibogama First Nations Council and the Nishnawbe Aski Nation. The First Nation's landbase is the 10806.5 ha Kasabonika Lake Reserve.
In September, 2007, the total registered population was 914, of which the on-reserve population was 866.